Plain-English translation of NCT06369285 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called combined with hormone therapy in people whose advanced breast cancer has progressed despite previous hormone treatments. The study will determine the best dose of to use alongside hormone therapy and will measure how well this combination works and how safe it is. Researchers also want to understand which patients are most likely to benefit from this treatment approach.
Many people with advanced hormone-positive breast cancer eventually stop responding to standard hormone treatments, leaving them with limited options. This medication targets a different pathway in cancer cells, and researchers hope that combining it with hormone therapy may help overcome treatment resistance and give patients more effective choices.
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You would be randomly assigned to take at one of three different doses, each combined with a hormone therapy medication chosen by your doctor. You would visit the study center regularly for check-ups, blood tests, and scans to monitor how the treatment is working and check for side effects. The study involves about 225 participants across multiple centers, and your participation would help determine the safest and most effective dose of this new treatment combination.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States