Plain-English translation of NCT06370845 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers want to understand how natural odors travel through your body when you breathe them in. This study will have you inhale either a real natural scent or a harmless placebo (fake scent) for 15 minutes, then collect a sample of cerebrospinal fluid—the fluid that surrounds your brain and spinal cord—to see if the scent made it there. The study compares people with obesity to people at a healthy weight to see if there are differences.
Scientists are curious about how our sense of smell connects to deeper parts of our body and brain. Understanding this pathway could eventually help doctors develop new treatments related to weight and metabolism.
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You will visit the hospital for a study visit that is timed with a spinal tap you already need for medical reasons. During your visit, you'll inhale either the natural scent or placebo through a small inhaler over 15 minutes, and a blood sample will also be collected. The researchers will then analyze your cerebrospinal fluid sample to see if the scent traveled there. The entire process is completed in one visit.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
Switzerland