Plain-English translation of NCT06370962 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Cystic Fibrosis research guide →Researchers want to understand how Kaftrio-Kalydeco, a newer medication for cystic fibrosis, affects children's sleep and their natural body rhythms (like being a morning or evening person). Some children with CF struggle with sleep problems and unusual sleep patterns, and doctors aren't sure whether the medication helps or changes these issues.
While this medication has helped many children breathe better and feel healthier, doctors have noticed something puzzling: some children still have sleep problems, and a small group actually experiences new sleep changes after starting treatment. This study aims to understand exactly how common these sleep issues are and whether they're connected to how the medication works in the body.
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You would visit one of the three participating cystic fibrosis centers for assessments related to your sleep and daily body rhythms. The study involves answering questions and possibly completing sleep-related tests or monitoring, though the exact details would be explained to you and your family by the research team. This is an observational study, meaning researchers are observing and measuring how you're doing rather than testing a new treatment.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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