Recruiting

Testing soluble fiber to help control childhood asthma

Plain-English translation of NCT06372249 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated June 2026 · How we translate trials

Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.

What is this trial?

Researchers want to understand whether increasing fiber intake—specifically through a supplement called Fruitafit —can help children with asthma breathe easier and have better disease control. The study looks at how fiber might change the bacteria in your gut, which scientists believe can influence asthma symptoms. Half of the children will receive the medication, and half will receive a placebo (a dummy pill that looks identical), so researchers can fairly compare how much the treatment actually helps.

Recent research suggests that what we eat affects the bacteria living in our gut, and these gut bacteria may play a role in asthma control. This trial aims to find out whether increasing fiber intake through this medication could be a safe, simple way to help more children manage their asthma better.

Do you qualify?

You likely qualify if…

you are between 6 and 17 years old
your child was diagnosed with asthma within the last 2 years
your child has signs of allergic airway inflammation (shown by a breathing test or allergy testing)
your child has not had an emergency room visit for asthma in the past month
your child can drink a liquid supplement and return for a follow-up visit 4–6 weeks later
your child does not follow a special or restricted diet

You likely don't qualify if…

your child has cystic fibrosis or bronchiectasis (other lung conditions)
your child's asthma medicines are expected to change in the next 4–6 weeks (except rescue inhalers)
your child currently eats 16 grams or less of fiber per day
your child is already enrolled in the study or your sibling is a participant

What participation looks like

Your child will visit the clinic twice over about 30 days. At the first visit, you'll answer questions about what your child ate in the last 24 hours, provide a nasal wash sample and blood sample, and answer questions about asthma control. Your child will then receive either the fiber supplement or a placebo and get instructions from a pharmacist on how to use it. Between visits, you'll collect three stool samples at home and mail them to a lab for analysis. At the second visit (about 3–4 weeks later), the same tests and questionnaires will be repeated. Your family will receive compensation for your time and some of the test results.

AI-generated summary from trial data · Jun 29, 2026 · Not medical advice

Trial locations(1 site)

United States

Phoenix Children's, Phoenix, Arizona