Plain-English translation of NCT06374537 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a structured, personalized exercise program can help people with advanced kidney disease or on dialysis regain strength and improve their quality of life. About 150 people will participate, with some doing twice-weekly exercise sessions for a year while others receive standard care without the exercise program. The researchers will measure how exercise affects participants' fitness, strength, and overall well-being.
People with advanced kidney disease and those on dialysis often become very weak and frail, which makes everyday activities harder and reduces their independence. This study is trying to find out if tailored exercise can safely reverse some of that weakness and improve how these patients feel and function.
You likely qualify if…
You likely don't qualify if…
If you're in the exercise group, you'll come to the training center twice a week for about 1 hour per session for 12 months, working with trainers on exercises tailored to your abilities. You'll also have three longer testing visits (at the start, 6 months, and 12 months) where you'll spend 2–3 hours completing fitness tests and health assessments. If you're in the comparison group, you'll have the same testing visits but no exercise sessions — this helps researchers see what improvement comes from the exercise alone.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
United States
Sponsor
University of Illinois at Chicago
Enrollment target
~150 participants
Started
May 2019
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ilaria Santi
University of Illinois at Chicago
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.