Plain-English translation of NCT06375213 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The INDE study is a long-term research project in Thailand designed to understand how memory and thinking problems develop over time. Researchers will collect blood, saliva, and sweat samples from nearly 1,000 participants—some with normal memory, others with mild memory problems, and others with dementia—to build a predictive model that could identify people at risk for cognitive decline. The goal is to find biomarkers (biological signs in your body) that help doctors diagnose and predict memory loss earlier.
Memory loss and dementia are growing health problems worldwide, but doctors don't yet have reliable ways to predict who will develop these conditions or how quickly they will decline. By studying a diverse group of Thai participants over several years, this research aims to identify early warning signs and develop tools that could help doctors intervene sooner and better understand the root causes of cognitive decline.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll attend an initial 4-hour visit where you'll answer questions about your health history, take memory and thinking tests, and provide samples of blood, saliva, and sweat. After that first visit, you'll return for follow-up visits every 1–2 years depending on your cognitive status (healthy participants every 2 years, those with mild memory problems yearly, those with dementia yearly). Throughout the study, researchers may share some of your biomarker results with you and offer counseling about what those results mean. The entire study lasts 2–8 years depending on which group you're in.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Thailand
Sponsor
King Chulalongkorn Memorial Hospital
Collaborators
Health Systems Research Institute,Thailand
Enrollment target
~990 participants
Started
August 2023
Primary completion
August 2035
Age range
35 Years and older
Last updated on clinicaltrials.gov in April 2024.
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Central contact
Poosanu Thanapornsangsuth, M.D.
Chulalongkorn University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.