Plain-English translation of NCT06376422 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Spongioflex®, a sterile bone implant designed to replace the part of your knee's natural cushioning (meniscus) that has been lost or damaged beyond repair. The implant is placed during arthroscopic surgery — a minimally invasive procedure using small cameras and instruments. Researchers want to see if this treatment reduces pain and prevents long-term knee damage in younger, active patients.
When part of the meniscus (the cartilage cushion in your knee) is lost or too damaged to repair, it can lead to arthritis and ongoing pain. There are no good non-surgical options once the damage is severe, so this trial is testing whether implanting a bone block can protect your knee and keep it functioning well for years to come.
You likely qualify if…
You likely don't qualify if…
If you join the surgery group, you will have arthroscopic surgery to implant the bone block, followed by a hospital stay of 2–3 days. You will then return for follow-up visits at 6 weeks, 6 months, 12 months, 2 years, and 5 years to check how well the implant is working and whether your knee pain and function have improved. If you are in the non-surgery comparison group, you will have follow-up visits at 6 months, 12 months, 2 years, and 5 years to track your symptoms without undergoing the procedure.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
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