Plain-English translation of NCT06376474 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Psoriasis research guide โPhase 1 โ Testing in a small group (usually 20โ80 people) to find a safe dose and watch for side effects.
This trial is testing how tablets work in people whose livers don't function normally. Researchers want to understand how the body processes this medication differently in people with mild or moderate liver damage compared to people with healthy livers. This information will help doctors figure out the right dose for patients with liver problems.
When your liver doesn't work well, it can change how your body processes medications. By studying this medication in people with different levels of liver damage, researchers can create safer, more effective treatment plans for psoriasis patients who also have liver problems.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You will come to a research clinic on one day and take a single dose of the study medication (60 mg in tablet form). The study team will then monitor you and take blood samples to see how your body processes the medication. The entire visit will likely take several hours, though the exact duration depends on the number of samples and tests required.
AI-generated summary from trial data ยท Jun 2, 2026 ยท Not medical advice
China
Phase
Safety & dosing
Sponsor
Ganzhou Hemay Pharmaceutical Co., Ltd
Enrollment target
~24 participants
Started
April 2024
Primary completion
December 2025
This trial's estimated completion date has passed โ the record may not be fully up to date.
Age range
18 Years โ 70 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Zimeng Wang
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.