Testing a medication to help thinking skills after brain radiation

This trial is testing whether metformin, a medication that has been used for many years to treat other conditions, can help protect memory and thinking skills in people who have received radiation therapy to their brain. Brain radiation can sometimes affect how well people think, remember, and concentrate. Researchers want to see if this medication might help prevent or reduce these changes.

Brain radiation therapy is an important treatment for brain tumors, but it can sometimes harm memory, attention, and other thinking abilities over time. There is no proven way to prevent this problem yet, so doctors are exploring whether this medication might help protect the brain.