Plain-English translation of NCT06377735 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a two-step treatment called bronchial arterial infusion plus bronchial arterial chemoembolization (BAI-BACE) for people with advanced squamous cell lung cancer located in the center of the chest. First, chemotherapy drugs are injected directly into blood vessels feeding the tumor to deliver high concentrations of medicine right where the cancer is. Then, the blood vessels supplying the tumor are sealed to cut off its blood supply. The procedure is designed to treat cancer with lower side effects than traditional chemotherapy.
Most people with advanced lung cancer cannot have surgery, and many fail to respond to standard chemotherapy and radiation treatments, leaving them with limited options. This trial is testing whether the direct injection and vessel-sealing approach can help people whose cancers have stopped responding to standard care.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo the BAI-BACE procedure, which involves your doctor injecting chemotherapy drugs directly into the blood vessels feeding your tumor and then sealing those vessels. You will need recent imaging scans within 2 weeks of starting treatment. The trial will track your health, tumor response, and any side effects over time to see if this treatment helps people with advanced lung cancer live longer and feel better.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
China