Plain-English translation of NCT06384963 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is the first human trial of a modified pacemaker technique called respiratory sinus arrhythmia (RSA) pacing. Researchers are testing whether special temporary pacing wires placed during your heart bypass surgery can be adjusted to match your breathing rhythm, which may help your weakened heart pump better over the days after surgery.
In a healthy heart, the heart rate naturally speeds up when you breathe in and slows down when you breathe out — this is called respiratory sinus arrhythmia. In people with severely weakened hearts, this natural rhythm is lost. This trial explores whether restoring this breathing-matched rhythm through pacing wires could improve heart function without added risk.
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After your bypass surgery, you will be randomly assigned to receive either the new breathing-matched pacing or standard pacing through temporary wires already placed on your heart during surgery. The pacing starts once you're breathing on your own (usually the day after surgery) and continues for up to 10 days or until you're ready to go home. During this time, your doctors will monitor your heart rhythm, heart function, and breathing patterns to see if the new pacing method is safe and helps your heart work better.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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