Plain-English translation of NCT06385275 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
Researchers at Boston University want to find out if vitamin K supplements can help people with knee arthritis. This is an early-stage study to test which form of vitamin K—and which dose—works best. The medication comes in three different versions, and researchers will measure how it affects your body's response to arthritis.
Doctors don't yet know the right type or amount of vitamin K needed to help people with knee arthritis. Some early research suggests this medication might help, but it hasn't been properly tested in older adults with your condition.
You likely qualify if…
You likely don't qualify if…
You will take one pill by mouth every day for 4 weeks. Depending on which group you're assigned to, your pill will contain one of three doses of vitamin K, or a placebo (inactive pill) with no medication. Researchers will likely draw blood before and after the 4 weeks to measure how the medication affects your body.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Sponsor
Boston University
Collaborators
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Enrollment target
~55 participants
Started
June 2025
Primary completion
December 2026
Age range
60 Years and older
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jean Liew, MD MS
Boston University Chobanian & Avedisian School of Medicine, Department of Rheumatology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.