Plain-English translation of NCT06385353 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research project is studying people who have just had their first deep vein thrombosis (DVT)—a blood clot in a leg vein. Researchers want to understand how the size and extent of the initial clot affects the chances of developing post-thrombotic syndrome, a condition where the leg remains swollen, painful, or uncomfortable long after the blood clot has formed. By tracking your recovery over six months with ultrasounds, blood tests, and symptom check-ins, doctors hope to predict who might develop these long-term problems and eventually find better ways to prevent them.
Many people who survive a leg blood clot experience lasting problems like chronic leg swelling and pain. Currently, doctors don't have a reliable way to predict who will develop these complications. This study aims to identify early warning signs—particularly by looking at how extensive the initial clot is—so that in the future, doctors can offer extra support or treatment to patients at highest risk.
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You will visit your doctor five times over six months—at one week, one month, three months, and six months after diagnosis. At each visit, your doctor will examine your leg for swelling and pain, and perform an ultrasound to see how the clot is healing. You'll also provide blood samples at the first four visits so researchers can study inflammation and clotting factors. At the three- and six-month visits, you'll fill out questionnaires about how the blood clot is affecting your daily life and quality of life. The entire study lasts six months and involves no experimental medication—just careful monitoring and measurement of your natural recovery.
AI-generated summary from trial data · Aug 30, 2026 · Not medical advice
France