Plain-English translation of NCT06386003 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Post Traumatic Stress Disorder research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , combined with a type of counseling called cognitive processing therapy, can help people with chronic post-traumatic stress disorder (PTSD) feel better. The study will give you one dose of the medication alongside 12 counseling sessions delivered over one week, plus two sessions to help prepare for and understand the medication experience.
Current treatments for PTSD don't work well enough for about half of all patients, leaving many people still struggling with their symptoms. Researchers believe this medication might help people process trauma more effectively during counseling, potentially improving outcomes for those who haven't benefited from standard care alone.
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Over one week, you would receive a single dose of the medication under medical supervision while participating in 12 counseling sessions designed to help you process trauma memories. You'll also have two additional sessions before and after to prepare for and reflect on the medication experience. During this week, you'll complete questionnaires about your mental health and wear a device to monitor your physical state. After the intensive week ends, you'll continue in a 12-week follow-up period where the research team monitors how you're doing.
AI-generated summary from trial data · Jun 29, 2026 · Not medical advice
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