Plain-English translation of NCT06386510 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called cranial nerve neuromodulation (tongue stimulation) combined with upper limb strength training to help people recover arm function after stroke. Researchers believe that stimulating the tongue nerve while doing arm exercises may help the brain rewire itself and improve movement and strength. The goal is to see if this combination is more effective than arm training alone.
Many people who have had a stroke continue to experience weakness in their arm that makes everyday tasks difficult and reduces independence. This trial exists to explore whether adding tongue stimulation to standard arm training can enhance the brain's natural ability to heal and recover.
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You will be randomly assigned to receive either real tongue stimulation or a sham (placebo) stimulation while performing upper limb strength training exercises. Over the study period, you will attend sessions where you complete arm strengthening exercises combined with the tongue stimulation treatment. The researchers will also use brain imaging and muscle testing to measure changes in your arm function and brain activity throughout the trial.
AI-generated summary from trial data · Aug 12, 2026 · Not medical advice
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