Plain-English translation of NCT06386588 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand whether gentle sounds played at just the right moment during sleep can help different parts of the brain work together better in people with schizophrenia. The study uses a special sleep headband that measures brain activity and plays soft tones during sleep. The goal is to see if this simple approach might improve memory and how brain regions communicate with each other.
People with schizophrenia often experience problems with memory and how their brain regions coordinate during sleep. This research explores whether timed sound stimulation during sleep could be a safe, non-medication way to strengthen brain networks and improve learning—something that hasn't been well tested yet.
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You will visit Massachusetts General Hospital for an MRI brain scan and complete a simple finger-tapping task. Then you'll wear a comfortable sleep headband at home for about a week—on some nights it will play soft sounds during your sleep, and on others it will just record your brain activity. You'll repeat the finger-tapping task twice at home during this week. Finally, you'll return for a second MRI scan to see if anything has changed. The entire study takes about 10 days.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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