Plain-English translation of NCT06388226 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a pilot study testing whether leg heat therapy can help people with heart failure with preserved ejection fraction (a condition where the heart doesn't pump as powerfully as it should). Researchers believe that warming the legs daily may improve blood flow and oxygen delivery to muscles, which could help you exercise longer and feel less tired. The study will compare the effects of warm leg heat therapy to a placebo control.
People with this type of heart failure often struggle with exercise and fatigue, and current treatments don't always help enough. This study explores whether a simple, non-invasive heat treatment could improve muscle function and physical fitness in ways that existing medications cannot.
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You will be given special water-circulating trousers connected to a heater, tank, and pump to use at home. Every day for 90 minutes, you will lie down (or sit, depending on your group) while warm water circulates through the trousers—either at a therapeutic temperature or a placebo temperature. You will also complete exercise tests at the clinic to measure how much your fitness improves over the study period.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States