Plain-English translation of NCT06388863 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing fecal microbiota transplantation (FMT)—a treatment that uses beneficial bacteria from healthy donors—to see if it can help relieve constipation in people with Parkinson's disease. About half of participants will receive capsules containing these healthy bacteria, while the other half will receive placebo capsules that look and smell identical but contain only milk powder. Researchers will track changes in constipation, other Parkinson's symptoms, mood, and quality of life over 24 weeks.
Constipation is a very common and distressing problem for people with Parkinson's disease, and current treatments don't work well for everyone. Early research suggests that changes in gut bacteria may play a role in Parkinson's symptoms, so this treatment is being studied to see if restoring healthy gut bacteria might help.
You likely qualify if…
You likely don't qualify if…
You will take 6 capsules twice a week for 24 weeks—either capsules containing healthy gut bacteria or identical-looking placebo capsules. Neither you nor the researchers will know which group you're in. During the study, you'll complete questionnaires about your constipation, Parkinson's symptoms, mood, and quality of life, and you'll provide stool and blood samples so researchers can study changes in your gut bacteria and measure your medication levels.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
China