Plain-English translation of NCT06389565 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a combination of talk therapy and a digital game called Change My Story can help young people living with HIV who are struggling with depression. Some participants will receive talk therapy alone, while others will also use the game, which helps you work through difficult feelings in a virtual environment. The researchers want to see which approach works best and is easiest for young people to stick with.
Young people with HIV often have depression and serious emotional distress, which makes it much harder for them to take their HIV medications regularly and stay engaged with their care. In many parts of the world, including Nigeria where this trial is happening, there simply aren't enough mental health specialists to help everyone who needs it—so this research is testing whether a game-based approach delivered through a phone or computer could fill that gap.
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You will be randomly assigned to either receive talk therapy sessions with an HIV counselor, or talk therapy plus access to the Change My Story game on your phone or computer. The talk therapy sessions will happen over several weeks, with a counselor helping you solve problems and cope with stress. If you're in the game group, you'll also have time to play and interact with the game between sessions. The researchers will check in with you throughout to see how you're feeling and whether the treatment is helping.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
Nigeria