Plain-English translation of NCT06392854 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers at Mayo Clinic are studying how (a hormone your body naturally makes) controls the release of fat from different regions of your body. They want to understand why some people store fat in the upper body and others in the lower body, and how this affects overall health. This is basic science research to help doctors better understand obesity and develop better treatments in the future.
Doctors know that where your body stores fat matters for your health, but they don't fully understand why some people store it around their belly (upper body) while others store it mainly in their hips and legs (lower body). Understanding how controls fat release in these different areas could help researchers develop better treatments for obesity and related health problems.
You likely qualify if…
You likely don't qualify if…
You will visit Mayo Clinic for a study visit where researchers will measure how much fat your body releases under different conditions. The study tests three different scenarios: two that slow down fat release and one that speeds it up. You'll have small measurements taken from different areas of your body to see how much fat is being released. The exact duration and number of visits will be explained during screening, but you should expect to spend time at their research facility for testing.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
Mayo Clinic
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~48 participants
Started
May 2024
Primary completion
June 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in April 2026.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.