Plain-English translation of NCT06394089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying unilateral biportal endoscopy—a minimally invasive spine surgery technique—to see how well it relieves leg pain and numbness caused by pinched nerves in the lower back. The research team wants to understand whether patients who have both pinched nerves and a small degree of vertebral slippage (called degenerative spondylolisthesis) get the same good results from this treatment as patients with pinched nerves alone.
Many people with pinched nerves in the lower back also have vertebral slippage, and doctors aren't certain whether minimally invasive surgery works as well for these patients. This trial aims to answer that question so doctors can better advise patients about whether this treatment is right for them.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be assigned to one of two groups based on whether you have vertebral slippage or not. You will undergo the minimally invasive spine surgery procedure at Beijing Friendship Hospital. After surgery, you will return for follow-up visits to complete assessments, imaging studies, and questionnaires about your pain, function, and quality of life. The study team will track your recovery and results over time to compare outcomes between the two groups.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
China
Sponsor
Beijing Friendship Hospital
Enrollment target
~150 participants
Started
March 2024
Primary completion
February 2027
Age range
50 Years – 80 Years
Last updated on clinicaltrials.gov in June 2025.
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Central contact
Xiang Li
Beijing Friendship Hospital
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