Plain-English translation of NCT06396416 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Many kidney transplant programs won't accept patients with obesity because of surgery risks. This study tests whether —a medication that helps with weight loss—combined with personalized nutrition advice and virtual coaching can help people with advanced kidney disease lose enough weight to qualify for transplant. This is a small test run to see if a larger study is feasible and safe.
Right now, 80% of kidney transplant programs in Canada exclude people with obesity, even though a transplant could save their lives. Weight loss is extremely difficult when managing both kidney disease and diabetes at the same time, and existing weight-loss programs are often too expensive or hard to follow. This medication has worked in other populations but has never been carefully studied in people with advanced kidney disease.
You likely qualify if…
You likely don't qualify if…
If you're chosen for the treatment group, you'll receive injections once a week for 6 months, along with personalized nutrition and movement advice and a virtual coaching session every 4 weeks. If you're in the comparison group, you'll continue your regular kidney and diabetes care. The entire study lasts 26 weeks, and researchers will track your weight, health, and how well you stick with the program.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
Canada