Plain-English translation of NCT06397677 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Rheumatoid Arthritis research guide →The MOUNTAIN study is looking for blood markers and imaging patterns that can help doctors predict which people with rheumatoid arthritis and interstitial lung disease will get worse over time. Researchers will collect blood samples, cheek swabs, lung imaging scans, and breathing tests from about 450 participants to identify these warning signs. By understanding these patterns better, doctors hope to catch disease progression earlier and help patients get treatment before their lungs are severely damaged.
Right now, doctors have difficulty predicting which rheumatoid arthritis patients will develop serious lung disease or get worse quickly. This study exists to find specific blood markers and imaging patterns that could serve as early warning signs, so treatment can start sooner and prevent lung damage before it becomes severe.
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You would visit the clinic at baseline and then again every 4 months for 2 years, with more detailed visits at year 1 and year 2. At each visit, you'll give blood samples, answer questionnaires about your health, and have your oxygen levels and breathing capacity checked. Some visits will also include lung imaging scans and a simple walking test — these are typically done as part of your regular medical care anyway. In total, the study tracks your disease over 2 years to see which patients develop worsening lung disease.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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