Plain-English translation of NCT06399653 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing non-invasive vagal nerve stimulation (nVNS)—a treatment that uses a small device placed on the neck to gently stimulate the vagus nerve—to help veterans with alcohol use disorder. The vagus nerve plays an important role in calming your nervous system and managing stress. Researchers believe that this treatment might help reduce withdrawal discomfort and cravings, making it easier to stay sober and improve your quality of life.
Alcohol use disorder is a serious problem affecting many veterans, and current treatments don't work well enough—more than half of people relapse within 6 months. The new treatment targets the underlying nervous system changes that drive alcohol cravings and withdrawal symptoms, which current medications don't fully address.
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You would attend a study visit where you receive the nerve stimulation treatment once and complete a brief pain task to help researchers understand how the device works. You would then take the device home and use it yourself twice a day for 7 days. After that week, you return for a follow-up visit where the researchers repeat some of the same assessments. The entire study lasts about 2 weeks.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
United States