Plain-English translation of NCT06399692 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
The RECHARGE: Women Trial is comparing two established surgical approaches to treat blocked coronary arteries in women: traditional open-heart bypass surgery (CABG) and a less invasive catheter-based procedure (PCI). Researchers want to understand which approach gives women the best long-term outcomes and quality of life.
Women are often underrepresented in heart disease research, and doctors don't always know which surgical approach is safest and most effective for women specifically. This trial aims to fill that gap by studying women's outcomes with both treatments over many years.
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If you enroll, you will be randomly assigned to receive either bypass surgery or the catheter-based procedure. After your procedure, you'll have phone check-ins at 30 days, 3 months, 6 months, and every 6 months for the first 3 years, then yearly check-ins through 10 years. You'll also have in-person visits for heart ultrasounds and blood tests at 1 year and as part of your regular care. Throughout the study, you'll complete questionnaires about your quality of life and symptoms.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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