Plain-English translation of NCT06400017 on ClinicalTrials.gov β Β· Source last updated Β· Translation generated Β· How we translate trials
This study doesn't follow the usual testing phases β it may be an observational study or a different type of research.
This trial is testing a surgical procedure called deep brain stimulation (DBS) to help people with Parkinson's disease who are experiencing memory and thinking problems. Researchers want to understand how stimulating a specific area of the brain called the substantia nigra can improve memory and cognitive function. Previous animal studies suggest this type of brain stimulation may help restore memory abilities in Parkinson's patients.
Memory and thinking problems affect up to 40% of Parkinson's patients at diagnosis and can progress to dementia in most patients within 10 years. This treatment aims to address these overlooked but serious symptoms that significantly reduce quality of life, and researchers want to understand exactly how the stimulation works to improve brain function.
You likely qualify ifβ¦
You likely don't qualify ifβ¦
If you qualify, you will undergo the planned DBS brain surgery at Beijing Tiantan Hospital. During surgery, researchers will test memory function while stimulating your brain at different settings and monitor your brain's electrical activity. You will also return for testing one month after surgery to evaluate how the stimulation affects your memory and brain network activity. The study involves behavioral memory tests and brain imaging to track changes in your cognitive function.
AI-generated summary from trial data Β· Jun 10, 2026 Β· Not medical advice
China