Testing a nasal spray for sudden migraine relief in people on prevention medicine

This trial is testing zavegepant, a nasal spray medication designed to quickly treat migraine attacks as they happen. The study focuses on people who are already taking a preventive migraine medication — a medicine that helps reduce how often migraines occur. Researchers want to understand how well the medication works and how well people tolerate it in this specific group of patients.

Migraine prevention medications help reduce how often attacks happen, but people still need a fast-acting treatment when an attack does occur. This trial investigates whether this medication provides that fast relief for people already using preventive treatments.