Plain-English translation of NCT06402617 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Atrial fibrillation is a condition where your heart rhythm becomes irregular, which can increase stroke risk and cause discomfort. This trial tests whether using a new mapping technology called RETRO-Mapping—combined with standard ablation treatment—can better identify and treat the specific areas of your heart causing the irregular rhythm. Half of participants will receive the standard treatment alone, and half will receive the standard treatment plus targeted ablation guided by the new mapping technology.
Current ablation treatment works well for some people but not others, and doctors don't fully understand why some patients continue to have irregular heartbeats even after standard treatment. This trial aims to see whether the new mapping technology can help identify hidden problem areas in the heart that might be driving the irregular rhythm, so they can be treated more precisely.
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You will undergo a catheter ablation procedure, which involves inserting thin tubes through your groin to reach your heart while you're under general anesthesia. All participants receive standard treatment to isolate the pulmonary veins (the source of many irregular heartbeats). If you're in the treatment group, your doctor will also use the new RETRO-Mapping technology to identify and treat additional problem areas in your heart. After the procedure, you'll be followed up to see how well your heart rhythm is controlled and whether the additional targeted treatment helps you stay in normal rhythm longer.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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