Plain-English translation of NCT06403475 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing transcutaneous vagus nerve stimulation (tVNS) — a safe, non-invasive technique that uses a small earpiece to stimulate a nerve in your ear — paired with computer-based speech therapy exercises. Researchers want to see if this combination can help people who had a stroke more than 6 months ago and now struggle with finding words or understanding language. About half of participants will receive the active treatment, and half will receive a sham (inactive) version, while both groups do the same speech exercises.
After a stroke, about 30% of survivors develop language problems that can last for years. While speech therapy helps, access to ongoing therapy is limited. This trial explores whether pairing nerve stimulation with speech exercises might boost recovery better than speech therapy alone, especially for people in the chronic phase of stroke recovery.
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You would come in for the study for 6 weeks, attending sessions 5 days a week for up to 45 minutes each day. During each session, you would wear a small earpiece device on your ear while completing computer-based speech and language exercises designed to help you practice finding words. Half of participants will have the device turned on (active stimulation), and half will have it in a non-active mode, but both groups will do the same exercises. The researchers will track how well you improve at finding words and using language in conversation.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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