Plain-English translation of NCT06406842 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During carotid endarterectomy (neck artery surgery to remove blockages), doctors sometimes miss small strokes that happen during the operation. This trial tests whether continuously monitoring how well your brain is getting oxygen during surgery — and adjusting your blood pressure and oxygen levels based on that information — can help prevent these hidden strokes. Half of the patients will have this special monitoring, while the other half will receive standard care.
Even after successful neck artery surgery, about 1 in 6 patients suffer small strokes that weren't caught at first. This happens because the brain's natural ability to protect itself can be disrupted during surgery. Doctors believe that monitoring brain oxygen in real time and making adjustments during the operation could help prevent these dangerous complications.
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If you join this trial, you will undergo carotid endarterectomy as planned, but you'll be randomly assigned to one of two groups. One group will have special brain oxygen monitoring during surgery with doctors adjusting your blood pressure and oxygen based on those readings; the other group will receive standard surgical care. The trial will follow 560 patients total, and researchers will track whether brain oxygen monitoring helps reduce the risk of post-surgery stroke.
AI-generated summary from trial data · Aug 12, 2026 · Not medical advice
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