Plain-English translation of NCT06409143 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called high-definition transcranial electrical stimulation (HD-tES)—a non-invasive way to stimulate specific areas of the brain using electrical currents applied to the scalp. The goal is to see whether this brain stimulation, when combined with standard upper-arm rehabilitation therapy, can help people who have had a stroke recover better arm and hand function. The study will test different stimulation patterns to find the most effective approach.
After a stroke, many people struggle to regain full use of their arm and hand, even with therapy. This new treatment aims to boost the brain's natural ability to heal and rewire itself by using targeted electrical stimulation, potentially making standard rehabilitation therapy more effective.
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Participants in the main trial will receive 10 minutes of brain stimulation (either to the affected or unaffected side of the brain, or both sides, depending on which group they're in) followed by 10 minutes of standard upper-arm rehabilitation exercises. They will repeat this combined treatment over several weeks while researchers monitor changes in brain activity and arm function using tests and brain imaging. The study includes both healthy volunteers (who help identify the best stimulation patterns) and stroke patients (who test whether these patterns actually improve recovery).
AI-generated summary from trial data · Jul 22, 2026 · Not medical advice
Taiwan