Plain-English translation of NCT06411353 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating why dialysis access points (called fistulae) sometimes fail in patients with end-stage kidney disease. Researchers will use imaging scans and computer models to understand how blood flows through these access points and what causes problems. The goal is to develop better ways to predict and prevent failures, so patients can keep their dialysis access working longer.
Dialysis access points are critical for kidney patients, but they fail too often and require repeated surgeries to create new ones. By understanding exactly how blood flows and what causes damage to these access points, doctors hope to identify problems earlier and improve long-term outcomes.
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You will have an initial screening visit, then undergo surgery to create your dialysis access point. After surgery, you will return for follow-up visits at regular intervals: within 2 weeks, at 3 months, 6 months, 1 year, and 2 years. During these visits, you will receive imaging scans (MRI and ultrasound) and possibly other monitoring tests to track how your access point is healing and how blood is flowing through it. The study lasts for 2 years after your surgery.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Italy
Sponsor
Mario Negri Institute for Pharmacological Research
Enrollment target
~15 participants
Started
March 2025
Primary completion
February 2028
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Michela Bozzetto
ASST Papa Giovanni XXIII
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.