Plain-English translation of NCT06413680 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Melanoma research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
This trial is testing a new drug called , which works by boosting your immune system to fight cancer. Researchers want to find the right dose and learn whether this medication works better on its own or when combined with another cancer drug called . The study will enroll about 240 patients with advanced cancers that have spread in their bodies.
Many patients with advanced cancers stop responding to current immune-boosting treatments. This trial explores whether adding a new medication that harnesses a different part of your immune system could help patients whose cancers have progressed despite other therapies.
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Depending on which part of the trial you join, you may receive the new medication alone or combined with another drug, given as injections or infusions. You will visit the clinic regularly for blood tests, scans, and physical exams to monitor how well the treatment works and check for side effects. The study has two phases: Phase 1 focuses on finding the right dose and is conducted in the United States, while Phase 2 tests the medication in specific cancer types globally and involves providing tissue samples before and during treatment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States