Plain-English translation of NCT06415591 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing auricular percutaneous electrical nerve field stimulation (PENFS) — a non-drug device therapy that delivers gentle electrical stimulation through patches placed on the ear — to see if it can reduce fibromyalgia pain and improve how well people function in daily life. Fibromyalgia is a chronic pain condition that affects millions of Americans and is particularly common in veterans. The researchers want to understand whether this treatment actually works better than a placebo and how it might change the way your brain processes pain.
With the ongoing opioid epidemic, doctors need better non-medication options to treat fibromyalgia, which is notoriously difficult to manage. Early studies suggest this electrical stimulation treatment may help, but larger rigorous studies are needed to confirm whether it truly works and to understand the science behind how it helps with pain.
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You will be randomly assigned to receive either the real electrical nerve stimulation patches or sham (fake) patches. Over 4 weeks, you'll visit the clinic 4 times and receive a new patch at each visit that you'll wear continuously at home for 5 days. The patches deliver gentle stimulation below the level you can feel. Some participants will also undergo brain imaging scans before, during, and after treatment to help researchers understand how the treatment affects your brain. Follow-up visits will continue for several weeks after your patches are finished.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States