Plain-English translation of NCT06420375 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This is a 12-week study testing whether a new medication called can safely and effectively treat mild ulcerative colitis. You'll take the medication for 4 weeks, then a placebo (a pill with no active ingredient) for 4 weeks, in random order. The study will also explore whether adding a one-time dose at the start helps improve results.
Current treatments don't work well enough for all patients with ulcerative colitis, and doctors are looking for new options that can reduce inflammation and symptoms more effectively.
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You'll visit the study site 7 times over 12 weeks. You'll take the study medication or placebo by mouth twice daily for 4 weeks, then switch to the other for 4 weeks. Some participants may also receive a single intravenous dose at the start. Throughout the study, you'll keep a log of your medications and have blood drawn, plus provide stool and urine samples for testing.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States