Plain-English translation of NCT06420700 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This trial is tracking patients who receive a combined procedure called gastric mucosal ablation with endoscopic sleeve gastroplasty. The procedure aims to help people lose weight by treating the stomach lining (which produces hunger signals) and then reshaping the stomach to be smaller, all done through the mouth without major surgery.
A smaller version of weight loss surgery called endoscopic sleeve gastroplasty hasn't worked as well as traditional surgical options. Researchers believe that adding treatment to reduce hunger signals in the stomach lining might make this less invasive approach more effective.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo the combined procedure at True You Weight Loss, which involves treating your stomach lining and reshaping your stomach in one endoscopic session (performed through your mouth, not open surgery). The study will track your progress and outcomes over time as part of a registry of patients receiving this procedure.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
United States
Sponsor
True You Weight Loss
Enrollment target
~100 participants
Started
January 2024
Primary completion
January 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in May 2024.
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Central contact
Chase Wooley, BS
True You Weight Loss
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.