Plain-English translation of NCT06421675 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called elranatamab, given as an injection under the skin, for patients whose multiple myeloma (a blood cancer) has returned or stopped responding to at least three different types of previous treatments. The study is designed to see if this medication works well when given at home as an outpatient, and whether the injection can be given less and less frequently over time as the disease improves.
Multiple myeloma is a serious blood cancer that often comes back or stops responding to standard treatments, leaving patients with limited options. This trial is testing whether this medication can offer hope to those with hard-to-treat disease, and whether giving it less frequently could make treatment easier and safer by reducing hospital visits and infection risk.
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You would receive injections of the medication under your skin, starting with a small dose that increases over the first week, then continuing as an outpatient at your local trial center. Initially you receive injections weekly, then every two weeks, then every four weeks if your disease improves. You must have a caregiver stay with you for the first 9 days after your first injection, and you need to live within 60 minutes of the hospital. You will be monitored closely for side effects and how well the treatment is working through blood tests and doctor visits for up to 3 years.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
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