Plain-English translation of NCT06423326 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a combination of three chemotherapy drugs—, , and —given before surgery for people with pancreatic cancer that doctors believe can be removed. The goal is to see if this medication shrinks the tumor and improves outcomes before surgery, and to understand how it affects the immune system's ability to fight cancer.
Pancreatic cancer is very serious, and surgery alone has not always been successful enough. Researchers want to know whether giving this treatment before surgery can make the tumor smaller and easier to remove, and whether it might help prevent the cancer from coming back.
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You would receive the three chemotherapy drugs through an IV on days 1 and 15 of each month for up to four months. During this time, you'll have regular CT or MRI scans, blood tests, and possibly a small biopsy to see how the treatment is working. After chemotherapy, you will have surgery to remove the tumor. Following surgery, you'll be followed up every 3 to 4 months for up to two years to monitor your health.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
United States