Plain-English translation of NCT06424288 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether , a new medication, works better for heart failure when combined with (a medication already approved for heart failure) compared to alone. You would take one tablet by mouth once daily, and researchers would track how the medication affects your heart failure symptoms and overall health over time.
Many people with heart failure still struggle with symptoms even while taking current treatments. This study aims to find out if this new medication could provide additional benefit when added to existing therapy.
You likely qualify if…
You likely don't qualify if…
You would take one tablet daily—either the new medication plus , or plus a placebo (inactive pill). You would visit your doctor regularly for check-ups, blood tests, and heart imaging, and the study team may contact you by phone to ask how you're feeling. The study continues until researchers have enough information to determine if the treatment is working, which could take months or longer.
AI-generated summary from trial data · Aug 23, 2026 · Not medical advice
United States