Plain-English translation of NCT06424288 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether , a new medication, works better when combined with (a medication already used for heart failure) compared to alone. You would take a pill once a day, and researchers would track how you feel and how your heart function changes over time. The goal is to see if this combination helps people with heart failure have fewer symptoms and better quality of life.
Many people with heart failure still struggle with symptoms even on current treatments. This medication is being tested to see if it offers an additional benefit when combined with existing heart failure drugs, potentially helping more patients manage their condition.
You likely qualify if…
You likely don't qualify if…
You would take a pill once daily—either the new medication combined with , or a placebo combined with (assigned by chance). You'll have regular doctor visits where your heart function will be checked, blood tests will be done, and you'll answer questions about how you're feeling. The study continues as long as the treatment is helping you and you're tolerating it well, with researchers monitoring you closely for any side effects.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
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