Plain-English translation of NCT06426173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether strength training exercises can help people with severe heart failure who are waiting for a heart transplant. Right now, patients waiting for transplants often spend a lot of time in bed, which can weaken their muscles and overall strength. The study wants to see if a supervised strength training program — done safely while you're in the hospital — can help you stay stronger and feel better.
People waiting for a heart transplant are often very ill and confined to bed rest, which can weaken their muscles and make it harder for them to recover after the transplant. Doctors believe that safe, supervised strength training might help prevent this muscle loss and improve quality of life, but this hasn't been studied carefully in transplant patients yet.
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If you join, you'll be randomly assigned to either receive strength training exercises plus your regular hospital care, or regular hospital care alone. You'll be tested at the start, after 6 weeks, and after 12 weeks to measure your strength, how far you can walk, how you feel, and certain heart markers in your blood. The strength training group will do supervised exercises while in the hospital — your doctors will make sure it's safe for your heart.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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