Plain-English translation of NCT06426693 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach called neurofeedback to help people with overweight or obesity reduce cravings for food. During the study, you'll have three brain imaging sessions where you'll see live information about your brain activity related to food cravings, and researchers will help you learn to control that activity. The hope is that this brain training will help you want food less and make healthier eating choices.
Many people with overweight or obesity struggle with intense cravings that make it hard to eat healthily, and current treatments don't work for everyone. This trial is exploring whether giving people real-time feedback about their own brain activity related to cravings could help them gain more control over those urges.
You likely qualify if…
You likely don't qualify if…
You would come in for three brain imaging appointments (fMRI scans). During each scan, you'll see real-time information about your brain activity related to food cravings, and researchers will guide you to try to modify that activity. Half of participants will receive real feedback, while the other half will receive a control feedback that doesn't contain the actual brain information—but you won't know which group you're in. Each visit involves lying still in an MRI scanner while viewing images and feedback on a screen.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States
Sponsor
Yale University
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~50 participants
Started
November 2024
Primary completion
March 2027
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kathleen A Garrison, PhD
Yale University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.