Plain-English translation of NCT06426810 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a newer surgical sealing system called LigaSure works better than traditional electrical sealing methods when removing sentinel lymph nodes during breast cancer surgery. The study focuses on patients who are at higher risk for complications like fluid buildup after surgery, including those with higher body weight or those who received chemotherapy before their operation. Researchers hope that this medication will reduce pain, hospital stays, and the need for follow-up drain procedures.
After breast cancer surgery, fluid buildup (called seroma) is a common problem that can cause discomfort, longer hospital stays, and sometimes serious infections requiring re-hospitalization. This study exists to see whether using a newer sealing technology during surgery can better prevent this complication compared to traditional methods.
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If you join this study, you would be randomly assigned to have your sentinel lymph node biopsy performed using either the newer LigaSure sealing system or the traditional electrical cautery method. Both groups would undergo the same breast-conserving surgery; only the method used to seal blood vessels and lymph vessels would differ. You would have a surgical drain placed to prevent fluid buildup, and the study team would monitor how quickly the drain can be removed and track any complications during your recovery.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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