Plain-English translation of NCT06427018 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →Researchers are studying two proteins called Ezrin and Pip5k1α that appear to be involved in asthma. This study will examine lung tissue samples from people with asthma and people without asthma to understand how these proteins work and whether blocking them might help control asthma symptoms better.
Current asthma medications don't work well for many patients—steroids help only 12% who use them correctly, and over half of people with asthma still struggle with symptoms even on combination medications. By understanding how these specific proteins contribute to asthma, researchers hope to develop new treatments with different approaches.
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If you qualify, your participation involves donating a small sample of lung tissue that is already being removed during a planned surgical procedure. The tissue is preserved and examined by researchers to study the two proteins. There are no additional visits or ongoing commitments—the study uses tissue that would otherwise be discarded.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Collaborators
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 6th People's Hospital
Enrollment target
~120 participants
Started
May 2024
Primary completion
December 2026
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lei-Miao Yin, MD
Yueyang Hospital, Shanghai University of Traditional Chinese medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.