Plain-English translation of NCT06427408 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how genes work in the placenta—the organ that nourishes your baby during pregnancy. This study will collect tiny tissue samples from your placenta twice: once in the first trimester (weeks 11–15) during a routine genetic screening biopsy, and again at delivery. By studying these samples using advanced genetic technology, scientists hope to map out how placenta cells change and communicate as pregnancy progresses.
The placenta is crucial for a healthy pregnancy, but scientists still don't fully understand how its cells develop and function over time. This research could help doctors better understand normal pregnancy, spot problems earlier, and improve care for pregnant people and babies.
You likely qualify if…
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If you're already having a chorionic villus biopsy for genetic screening between weeks 11 and 15, the research team will ask you to join this study. After your biopsy, a small tissue sample will be frozen and saved for genetic analysis. Then, when you deliver your baby (whether by cesarean section or vaginal delivery), another small placenta sample will be collected and frozen. The frozen samples will later be analyzed using advanced technology to study how genes are expressed in placenta cells over time.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
France
Sponsor
Assistance Publique - Hôpitaux de Paris
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France, URC-CIC Paris Descartes Necker Cochin
Enrollment target
~100 participants
Started
March 2026
Primary completion
November 2028
Age range
18 Years – 50 Years
Sex
Female only
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Vassilis TSATSARIS, MD PHD
Institut National de la Santé Et de la Recherche Médicale, France
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.