Plain-English translation of NCT06428617 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This is a research registry—a long-term tracking study—for adults with obesity who are having a gastric fundus mucosal ablation (GFMA) procedure. GFMA is a minimally invasive endoscopic procedure that aims to reduce hunger by damaging the part of your stomach lining that produces ghrelin, a hormone that signals hunger. The study will follow up to 200 patients at two True You Weight Loss locations to collect information about weight loss, health improvements, and any side effects.
Obesity is a chronic disease that can lead to serious health problems. This treatment is designed to reduce hunger signals in the brain, helping people lose weight more effectively. The research aims to understand how well this new treatment works in real-world practice and whether it's safe for patients long-term.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will receive the gastric fundus ablation procedure as planned, and the study will simply track your progress during regular follow-up visits. At each visit, your weight will be measured and any side effects will be documented. You will also follow a comprehensive lifestyle program with nutritional support and dietary guidance. The study collects this information over time to understand how well the procedure works and whether it helps improve weight-related health conditions.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States
Sponsor
True You Weight Loss
Enrollment target
~200 participants
Started
June 2024
Primary completion
June 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in April 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Chase Wooley, BS
True You Weight Loss
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.