Can eating within set time windows help memory problems?

Plain-English translation of NCT06429124 on ClinicalTrials.gov ↗ · Source last updated June 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This is a pilot study looking at whether time-restricted eating—eating all your meals within an 8-hour window and fasting for 16 hours—might help improve memory and thinking problems in people with mild cognitive impairment. Researchers want to see if this eating pattern is practical for patients to follow and whether it leads to improvements in memory, attention, and overall brain health.

Mild cognitive impairment can sometimes progress to dementia, and doctors are looking for safe, simple lifestyle changes that might slow down or prevent this decline. This treatment approach is based on earlier research suggesting that fasting periods may help the brain.

Do you qualify?

You likely qualify if…

you are between 55 and 89 years old
you have been diagnosed with mild cognitive impairment using Mayo Clinic criteria
you have a family member or spouse willing to be your study partner and attend visits with you
you have access to the internet and can speak and read English (or have a family member who can help with translations)
you have been on any memory medications at a stable dose for at least 3 months

You likely don't qualify if…

you have diabetes that requires insulin injections or is not well controlled
you have an eating disorder
you have severe dementia or a score of 9 or below on the memory screening test
you are taking prescription medications twice daily that must be taken with food
you naturally eat within a window smaller than 11 hours on 3 or more days per week

What participation looks like

You will be asked to eat all your meals within an 8-hour window and fast for 16 hours, about 5 days per week for 3 months. You'll attend individual and group coaching sessions where staff will teach you about the eating pattern, answer your questions, and help you stay on track. You'll also complete memory and thinking tests, have blood drawn to check your health markers, and answer questions about your well-being at the start and end of the 3 months.

AI-generated summary from trial data · Jun 8, 2026 · Not medical advice

Can eating within set time windows help memory problems?

What is this trial?

Do you qualify?

What participation looks like

Trial locations