Plain-English translation of NCT06429579 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a research study for children aged 6 months to 18 years with severe pulmonary artery hypertension—a serious condition where blood pressure in the lungs becomes dangerously high. The study compares two groups: children who receive a surgical procedure called a Potts-shunt along with standard medicines, and children who receive only the standard medicines. The goal is to see whether the combination of surgery and medication helps children feel better, grow normally, and avoid needing a lung transplant over 3 years of follow-up.
Even when children take multiple heart medications for severe pulmonary hypertension, many still get worse and may need a lung transplant. Doctors want to know if adding a surgical procedure can help these children do better and stay healthier for longer.
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If you join this study, you will be placed into one of two groups based on your doctor's recommendation and your family's preferences: one group receiving the surgical procedure plus medications, and the other receiving medications only. You will have 8 follow-up visits over 3 years—at the time of surgery (or when you start medications), during the recovery period, and then at 1 month, 3 months, 6 months, 1 year, 2 years, and 3 years. At each visit, doctors will check your health, do heart tests, and monitor how well the treatment is working.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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