Plain-English translation of NCT06436053 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This trial is testing a pacemaker feature called SyncAV that automatically adjusts the timing between the upper and lower chambers of your heart. Researchers want to see if this new automatic timing feature works well when combined with a special type of pacemaker lead placement called left bundle branch area pacing. If it works, this could help heart failure patients feel better and live longer.
Many heart failure patients have electrical problems that make their heart's chambers beat out of sync. While pacemakers can help, doctors currently have to manually adjust the timing between heartbeats. This study explores whether an automatic adjustment feature could make pacemakers work better without needing constant manual fine-tuning.
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If you join this study, you will receive an Abbott pacemaker system with the SyncAV feature implanted in a surgical procedure. After implantation, researchers will monitor how well the new automatic timing feature works by measuring your heart's electrical activity and how you feel. You'll need to attend follow-up visits and comply with all study requirements, though the exact number and timing of visits should be discussed with the research team.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Italy
Sponsor
Abbott Medical Devices
Enrollment target
~50 participants
Started
May 2024
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nima Badie, PhD
Abbott Medical Devices
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.