Plain-English translation of NCT06438445 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether royal jelly—a nutrient-rich substance made by bees—can help reduce inflammation and slow cellular aging in people with chronic kidney disease who need dialysis. Researchers believe the medication contains natural compounds that might protect kidney dialysis patients from some of the complications of their condition. The study will compare how participants respond to the medication versus a placebo (dummy pill) over several months.
People on dialysis often suffer from excessive inflammation and premature aging of their cells, which can worsen their kidney disease and overall health. Currently, there are no proven treatments using royal jelly for these specific problems, so researchers want to see if this natural supplement could help.
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You would take either the royal jelly supplement or a placebo capsule (500 mg) once per day for 8 weeks. After that, there would be an 8-week break called a 'washout period,' and then you would switch to whichever you didn't receive the first time for another 8 weeks. Blood and stool samples would be collected before and after each treatment period so researchers can measure changes in inflammation and cellular health.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
Brazil
Sponsor
Universidade Federal Fluminense
Enrollment target
~30 participants
Started
July 2024
Primary completion
December 2026
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Denise Mafra
Universidade Federal Fluminense
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.