Plain-English translation of NCT06441123 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new family of HIV latency regulators (LRAs) — experimental compounds designed to wake up hidden HIV that remains dormant in immune cells, even when your viral load is undetectable. Researchers will take a small blood sample from you, isolate your immune cells in the lab, and treat them with these new compounds to see how well they work at activating the hidden virus.
Even when HIV treatment keeps your viral load undetectable, the virus can hide silently in your immune cells. This research aims to develop better ways to wake up that hidden virus so your body's immune system can find and destroy it — potentially bringing us closer to a cure.
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Your involvement is straightforward and one-time. You'll visit the research center for a single appointment where researchers will draw about 20 milliliters of blood (roughly 4 teaspoons) — similar to a routine blood test. That blood will be sent to the lab, where your immune cells will be isolated and exposed to the new compounds for about 18 to 20 hours. You won't need to take any medication or return for follow-up visits; the study happens entirely in the laboratory.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
France
Collaborators
Centre National de la Recherche Scientifique, France, Université Montpellier
Enrollment target
~24 participants
Started
February 2025
Primary completion
February 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alain MAKINSON, Pr
University Hospital, Montpellier
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.